Sexual reproduction is a form of reproduction where two morphologically distinct types of specialized reproductive cells called gametes fuse together, involving a female's large ovum (or egg) and a male's smaller sperm. Each gamete contains half the number of chromosomes of normal cells. They are created by a specialized type of cell division, which only occurs in eukaryotic cells, known as meiosis. The two gametes fuse during fertilization to produce DNA replication and the creation of a single-celled zygote which includes genetic material from both gametes. In a process called genetic recombination, genetic material (DNA) joins up so that homologous chromosome sequences are aligned with each other, and this is followed by exchange of genetic information. Two rounds of cell division then produce four daughter cells with half the number of chromosomes from each original parent cell, and the same number of chromosomes as both parents, though self-fertilization can occur. For instance, in human reproduction each human cell contains 46 chromosomes, 23 pairs, except gamete cells, which only contain 23 chromosomes, so the child will have 23 chromosomes from each parent genetically recombined into 23 pairs. Cell division initiates the development of a new individual organism in multicellular organisms, including animals and plants, for the vast majority of whom this is the primary method of reproduction. A species is defined as a taxonomic rank. A species is often defined as the largest group of organisms where two hybrids are capable of reproducing fertile offspring, typically using sexual reproduction, although the species problem encompasses a series of difficult related questions that often come up when biologists define the word species.