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Definition of Frank-starling law of the heart

Frank-starling law of the heart Definition from Medicine Dictionaries & Glossaries
Aging Hearts and Arteries Glossary
A phenomenon in which the more the heart muscle is stretched the more vigorously it contracts.
Source: National Institute on Aging
Frank-starling law of the heart Definition from Encyclopedia Dictionaries & Glossaries
English Wikipedia - The Free Encyclopedia
The Frank–Starling law of the heart (also known as Starling's law or the Frank–Starling mechanism or Maestrini heart's law) states that the stroke volume of the heart increases in response to an increase in the volume of blood filling the heart (the end diastolic volume) when all other factors remain constant. The increased volume of blood stretches the ventricular wall, causing cardiac muscle to contract more forcefully (the so-called Frank–Starling mechanisms). The stroke volume may also increase as a result of greater contractility of the cardiac muscle during exercise, independent of the end-diastolic volume. The Frank–Starling mechanism appears to make its greatest contribution to increasing stroke volume at lower work rates, and contractility has its greatest influence at higher work rates.

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