Definition of Ag-013736
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Ag-013736 Definition from Medicine Dictionaries & Glossaries
NCI Dictionary of Cancer Terms
A substance that is being studied in the treatment of cancer. It belongs to thefamilies of drugs called angiogenesis inhibitors and protein tyrosine kinase inhibitors.A Service of the National Cancer Institute.
Ag-013736 Definition from Encyclopedia Dictionaries & Glossaries
English Wikipedia - The Free Encyclopedia
Axitinib (AG013736; trade name Inlyta) is a small molecule tyrosine kinase inhibitor developed by Pfizer. It has been shown to significantly inhibit growth of breast cancer in animal (xenograft) models and has shown partial responses in clinical trials with renal cell carcinoma (RCC) and several other tumour types. It was approved by the U.S. Food and Drug Administration after showing a modest increase in progression-free survival, though there have been reports of fatal adverse effects.
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