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Definition of Abi-007

Abi-007 Definition from Medicine Dictionaries & Glossaries
NCI Dictionary of Cancer Terms
A substance that is being studied in the treatment of cancer. It is a special form of the anticancer drug paclitaxel that may have fewer side effects and may be able to be given in higher doses. It belongs to the families of drugs called mitotic inhibitors and taxanes.  
A Service of the National Cancer Institute.
Abi-007 Definition from Encyclopedia Dictionaries & Glossaries
English Wikipedia - The Free Encyclopedia
Protein-bound paclitaxel, also known as nanoparticle albumin–bound paclitaxel or nab-paclitaxel, is an injectable formulation of paclitaxel used to treat breast cancer, lung cancer and pancreatic cancer, among others. Paclitaxel destroys cancer cells by preventing the normal breakdown of microtubules during cell division. In this formulation, paclitaxel is bonded to albumin as a delivery vehicle. It is manufactured and sold in the United States by Abraxis BioScience under the trade name Abraxane where it is designated as an orphan drug as first-line treatment, in combination with gemcitabine, for the orphan disease "metastatic adenocarcinoma of the pancreas."

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